Mini-IVF (Minimal Stimulation IVF) – Semi-Natural Cycle

Mini-IVF is a mild stimulation in-vitro fertilization (IVF) approach that uses minimal or no hormonal medication to stimulate the ovaries. Unlike conventional IVF, which aims to retrieve a high number of eggs, Mini-IVF focuses on retrieving fewer but higher-quality eggs to maximize the chances of pregnancy.

How Does the Mini-IVF Process Work?

Mini-IVF follows the same steps as a natural IVF cycle, with the difference of using a small amount of fertility medication to support the growth and maturation of follicles.

1. Mild Ovarian Stimulation:

1. • Small doses of medication may be used to stimulate the ovaries, preventing premature ovulation and ensuring the best-quality eggs.

2. Egg Retrieval (Oocyte Pick-Up):

1. • Typically, 1-3 high-quality eggs are retrieved compared to 7-15 eggs in conventional IVF, where only a fraction may be of good quality.

3. Fertilization:

1. • The retrieved eggs are fertilized in the laboratory using either traditional IVF or ICSI (Intracytoplasmic Sperm Injection).

4. Embryo Transfer or Cryopreservation:

1. • The best embryo(s) are either transferred to the uterus or frozen for future use.

Benefits of Mini-IVF:

✔ Lower risk of ovarian hyperstimulation syndrome (OHSS)
✔ Fewer hormone injections – reducing discomfort and side effects
✔ More cost-effective than conventional IVF
✔ Lower risk of multiple pregnancies (as fewer eggs are retrieved and transferred)
✔ Ideal for women with low ovarian reserve (who may not respond well to high-dose hormone stimulation)
✔ Can be repeated in successive cycles, collecting multiple eggs over time

Who Can Benefit from Mini-IVF?

✔ Women with poor ovarian response in previous IVF cycles
✔ Those who prefer a more natural approach with fewer hormones
✔ Women who cannot or do not want to take high doses of fertility drugs
✔ Couples looking for a more affordable fertility treatment

Mini-IVF is a promising alternative for women seeking a gentler, more affordable, and less invasive IVF experience, while still maintaining high success rates.